• High Blood Pressure Drug-Induced Toothache

    High Blood Pressure Drug-Induced Toothache

    In what is believed to be the first reported case of its kind, a drug used to manage high blood pressure caused a 45-year old man to develop a toothache after each dose.

    The man had been diagnosed with type 2 diabetes for eight years and hypertension for five years.  After switching his high blood pressure drug for one that was better for kidney protection, he noticed a throbbing toothache about 30 minutes after taking his first dose.  He rated the pain level a 7 out of 10.  His pain was completely gone about two hours after omitting the next dose.  Over the following week, his tooth pain returned at the same post-dose interval every day.

    The man underwent an exam and panoramic x-ray, which showed no visible dental lesion.  The symptoms resolved after he stopped taking the medication.

    Things to Consider

    Experiencing pain after every dose of a medication which then vanishes on withdrawal should undergo a thorough prescription review before undergoing invasive dental procedures.

    Losartan potassium was the medication referred to in this case report published in Frontiers of Pharmacology.

    Dr. Bicuspid

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